TGF beta Receptor III (TGFBR3) Human Gene Knockout Kit (CRISPR)

CAT#: KN216595RB

TGFBR3 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


TGFBR3 mouse monoclonal antibody,clone OTI4F11
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TGFBR3 (Myc-DDK-tagged)-Human transforming growth factor, beta receptor III (TGFBR3), transcript variant 1
    • 10 ug

CNY 9,344.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol TGF beta Receptor III
Locus ID 7049
Kit Components

KN216595G1, TGF beta Receptor III gRNA vector 1 in pCas-Guide CRISPR vector

KN216595G2, TGF beta Receptor III gRNA vector 2 in pCas-Guide CRISPR vector

KN216595RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001195683, NM_001195684, NM_003243, NR_036634
Synonyms betaglycan; BGCAN
Summary This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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