beta 1 Adrenergic Receptor (ADRB1) Human Gene Knockout Kit (CRISPR)

CAT#: KN217134LP

ADRB1 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit Polyclonal Anti-ADRB1 Antibody
    • 100 ul

CNY 5,250.00


ADRB1 (Myc-DDK-tagged)-Human adrenergic, beta-1-, receptor (ADRB1)
    • 10 ug

CNY 5,488.00

Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol beta 1 Adrenergic Receptor
Locus ID 153
Kit Components

KN217134G1, beta 1 Adrenergic Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN217134G2, beta 1 Adrenergic Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN217134LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000684
Synonyms ADRB1R; B1AR; BETA1AR; RHR
Summary The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

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