Desmoplakin (DSP) Human Gene Knockout Kit (CRISPR)

CAT#: KN218822RB

DSP - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit Polyclonal Anti-DSP Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


DSP (Myc-DDK-tagged)-Human desmoplakin (DSP), transcript variant 1
    • 10 ug

CNY 18,608.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Desmoplakin
Locus ID 1832
Kit Components

KN218822G1, Desmoplakin gRNA vector 1 in pCas-Guide CRISPR vector

KN218822G2, Desmoplakin gRNA vector 2 in pCas-Guide CRISPR vector

KN218822RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001008844, NM_001319034, NM_004415
Synonyms DCWHKTA; DP; DPI; DPII
Summary This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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