Delta Opioid Receptor (OPRD1) Human Gene Knockout Kit (CRISPR)
CAT#: KN219275LP
OPRD1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Delta Opioid Receptor |
Locus ID | 4985 |
Kit Components |
KN219275G1, Delta Opioid Receptor gRNA vector 1 in pCas-Guide CRISPR vector KN219275G2, Delta Opioid Receptor gRNA vector 2 in pCas-Guide CRISPR vector KN219275LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000911 |
Synonyms | OPRD |
Summary | G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN219275 | OPRD1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN219275BN | OPRD1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN219275RB | OPRD1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN419275 | OPRD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA103322 | OPRD1 CRISPRa kit - CRISPR gene activation of human opioid receptor delta 1 |
CNY 12,255.00 |
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