Dopamine Transporter (SLC6A3) Human Gene Knockout Kit (CRISPR)

CAT#: KN219466RB

SLC6A3 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Mouse Monoclonal SLC6A3/DAT1 Antibody (mAb16)
    • 100 ul

CNY 5,381.00


SLC6A3 (Myc-DDK-tagged)-Human solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (SLC6A3)
    • 10 ug

CNY 4,616.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Dopamine Transporter
Locus ID 6531
Kit Components

KN219466G1, Dopamine Transporter gRNA vector 1 in pCas-Guide CRISPR vector

KN219466G2, Dopamine Transporter gRNA vector 2 in pCas-Guide CRISPR vector

KN219466RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001044
Synonyms DAT; DAT1; PKDYS
Summary This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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