UBE2G2 (NM_003343) Human Mass Spec Standard

Specifications

Product Data
Description	UBE2G2 MS Standard C13 and N15-labeled recombinant protein (NP_003334)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200407
Predicted MW	18.6 kDa
Protein Sequence	Sequence Link (showhide) >RC200407 protein sequence Red=Cloning site Green=Tags(s) MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPK MRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDA SKMWRDDREQFYKIAKQIVQKSLGL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003334
RefSeq Size	3400
RefSeq ORF	495
Synonyms	UBC7
Locus ID	7327
Cytogenetics	21q22.3
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Protein Families	Druggable Genome
Protein Pathways	Parkinson's disease, Ubiquitin mediated proteolysis

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