Necdin (NDN) (NM_002487) Human Mass Spec Standard

Specifications

Product Data
Description	NDN MS Standard C13 and N15-labeled recombinant protein (NP_002478)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200448
Predicted MW	36.1 kDa
Protein Sequence	Sequence Link (showhide) >RC200448 protein sequence Red=Cloning site Green=Tags(s) MSEQSKDLSDPNFAAEAPNSEVHSSPGVSEGVPPSATLAEPQSPPLGPTAAPQAAPPPQAPNDEGDPKAL QQAAEEGRAHQAPSAAQPGPAPPAPAQLVQKAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSIL RRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDRVALSNRMPMTGLLLMILSLIYVKGRGARESAV WNVLRILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLA RVFKKDPQAWPSRYREALEEARALREANPTAHYPRSSVSED TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002478
RefSeq Size	1897
RefSeq ORF	963
Synonyms	HsT16328; PWCR
Locus ID	4692
Cytogenetics	15q11.2
Summary	This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic neurons. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transcription Factors

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