RNase H1 (RNASEH1) (NM_002936) Human Mass Spec Standard

CAT#: PH300595

RNASEH1 MS Standard C13 and N15-labeled recombinant protein (NP_002927)



  View other "RNase H1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description RNASEH1 MS Standard C13 and N15-labeled recombinant protein (NP_002927)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200595
Predicted MW 32.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002927
RefSeq Size 1865
RefSeq ORF 858
Synonyms H1RNA; PEOB2; RNH1
Locus ID 246243
Cytogenetics 2p25.3
Summary This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]
Protein Pathways DNA replication
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