HNRNPD (NM_002138) Human Mass Spec Standard

CAT#: PH300660

HNRNPD MS Standard C13 and N15-labeled recombinant protein (NP_002129)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description HNRNPD MS Standard C13 and N15-labeled recombinant protein (NP_002129)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200660
Predicted MW 32.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002129
RefSeq Size 2110
RefSeq ORF 918
Synonyms AUF1; AUF1A; hnRNPD0; HNRPD; P37
Locus ID 3184
Cytogenetics 4q21.22
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transcription Factors
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