DNA Polymerase epsilon (POLE3) (NM_017443) Human Mass Spec Standard

Specifications

Product Data
Description	POLE3 MS Standard C13 and N15-labeled recombinant protein (NP_059139)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200874
Predicted MW	16.9 kDa
Protein Sequence	Sequence Link (showhide) >RC200874 protein sequence Red=Cloning site Green=Tags(s) MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVL SAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQN EEEEVDN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_059139
RefSeq Size	2288
RefSeq ORF	441
Synonyms	CHARAC17; CHRAC2; CHRAC17; p17; YBL1
Locus ID	54107
Cytogenetics	9q32
Summary	POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]
Protein Pathways	Base excision repair, DNA replication, Metabolic pathways, Nucleotide excision repair, Purine metabolism, Pyrimidine metabolism

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.