p23 (PTGES3) (NM_006601) Human Mass Spec Standard

Specifications

Product Data
Description	PTGES3 MS Standard C13 and N15-labeled recombinant protein (NP_006592)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201254
Predicted MW	18.7 kDa
Protein Sequence	Sequence Link (showhide) >RC201254 protein sequence Red=Cloning site Green=Tags(s) MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTD RSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPE VDGADDDSQDSDDEKMPDLE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006592
RefSeq Size	2045
RefSeq ORF	480
Synonyms	cPGES; P23; TEBP
Locus ID	10728
Cytogenetics	12
Summary	This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]
Protein Families	Druggable Genome, Nuclear Hormone Receptor

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