MOBK1B (MOB1A) (NM_018221) Human Mass Spec Standard

Specifications

Product Data
Description	MOBKL1B MS Standard C13 and N15-labeled recombinant protein (NP_060691)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201487
Predicted MW	24.9 kDa
Protein Sequence	Sequence Link (showhide) >RC201487 representing NM_018221 Red=Cloning site Green=Tags(s) MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINM LYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPF PKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEK LGSKDR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060691
RefSeq Size	2543
RefSeq ORF	648
Synonyms	C2orf6; MATS1; MOB1; Mob4B; MOBK1B; MOBKL1B
Locus ID	55233
Cytogenetics	2p13.1
Summary	The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Protein Families	Druggable Genome

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