NDUFA5 (NM_005000) Human Mass Spec Standard

Specifications

Product Data
Description	NDUFA5 MS Standard C13 and N15-labeled recombinant protein (NP_004991)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201539
Predicted MW	13.5 kDa
Protein Sequence	Sequence Link (showhide) >RC201539 protein sequence Red=Cloning site Green=Tags(s) MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLED QLQGGQLEEVILQAEHELNLARKMREWKLWEPLVEEPPADQWKWPI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004991
RefSeq Size	5602
RefSeq ORF	348
Synonyms	B13; CI-13kB; CI-13KD-B; NUFM; UQOR13
Locus ID	4698
Cytogenetics	7q31.32
Summary	This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014]
Protein Pathways	Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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