CYB5R3 (NM_000398) Human Mass Spec Standard

CAT#: PH301592

CYB5R3 MS Standard C13 and N15-labeled recombinant protein (NP_000389)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CYB5R3 MS Standard C13 and N15-labeled recombinant protein (NP_000389)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201592
Predicted MW 34.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000389
RefSeq Size 2923
RefSeq ORF 903
Synonyms B5R; DIA1
Locus ID 1727
Cytogenetics 22q13.2
Summary This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
Protein Families Druggable Genome
Protein Pathways Amino sugar and nucleotide sugar metabolism
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