SPINT2 (NM_021102) Human Mass Spec Standard

Specifications

Product Data
Description	SPINT2 MS Standard C13 and N15-labeled recombinant protein (NP_066925)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202044
Predicted MW	28.2 kDa
Protein Sequence	Sequence Link (showhide) >RC202044 protein sequence Red=Cloning site Green=Tags(s) MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGG CDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTG PCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVLLAGLFVMVLI LFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_066925
RefSeq Size	1817
RefSeq ORF	756
Synonyms	DIAR3; HAI-2; HAI2; Kop; PB
Locus ID	10653
Cytogenetics	19q13.2
Summary	This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Protein Families	Transmembrane

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.