TFPI (NM_001032281) Human Mass Spec Standard

CAT#: PH302098

TFPI MS Standard C13 and N15-labeled recombinant protein (NP_001027452)



  View other "TFPI" proteins (6)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description TFPI MS Standard C13 and N15-labeled recombinant protein (NP_001027452)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202098
Predicted MW 28.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001027452
RefSeq Size 1166
RefSeq ORF 753
Synonyms EPI; LACI; TFI; TFPI1
Locus ID 7035
Cytogenetics 2q32.1
Summary This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Protein Families Secreted Protein
Protein Pathways Complement and coagulation cascades
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