LIMPII (SCARB2) (NM_005506) Human Mass Spec Standard

CAT#: PH302162

SCARB2 MS Standard C13 and N15-labeled recombinant protein (NP_005497)



  View other "LIMPII" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of scavenger receptor class B, member 2 (SCARB2)
    • 100 ug

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Rabbit Polyclonal LIMPII/lpg85 Antibody
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Specifications

Product Data
Description SCARB2 MS Standard C13 and N15-labeled recombinant protein (NP_005497)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202162
Predicted MW 54.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005497
RefSeq Size 4780
RefSeq ORF 1434
Synonyms AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII
Locus ID 950
Cytogenetics 4q21.1
Summary The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome
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