Nucleoside Diphosphate Kinase 7 (NME7) (NM_197972) Human Mass Spec Standard

Specifications

Product Data
Description	NME7 MS Standard C13 and N15-labeled recombinant protein (NP_932076)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202669
Predicted MW	42.5 kDa
Protein Sequence	Sequence Link (showhide) >RC202669 protein sequence Red=Cloning site Green=Tags(s) MNHSERFVFIAEWYDPNASLLRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFS RQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDH QSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDS FASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVN VEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKI QNAVHCTDLPEDGLLEVQYFFKILDN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_932076
RefSeq Size	1625
RefSeq ORF	1131
Synonyms	CFAP67; MN23H7; NDK 7; NDK7; nm23-H7
Locus ID	29922
Cytogenetics	1q24.2
Summary	This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Purine metabolism, Pyrimidine metabolism

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