NDUFA2 (NM_002488) Human Mass Spec Standard

Specifications

Product Data
Description	NDUFA2 MS Standard C13 and N15-labeled recombinant protein (NP_002479)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202715
Predicted MW	10.9 kDa
Protein Sequence	Sequence Link (showhide) >RC202715 protein sequence Red=Cloning site Green=Tags(s) MAAAAASRGVGAKLGLREIRIHLCQRSPGSQGVRDFIEKRYVELKKANPDLPILIRECSDVQPKLWARYA FGQETNVPLNNFSADQVTRALENVLSGKA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002479
RefSeq Size	726
RefSeq ORF	297
Synonyms	B8; CD14; CIB8; MC1DN13
Locus ID	4695
Cytogenetics	5q31.3
Summary	The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Protein Pathways	Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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