PAM16 (NM_016069) Human Mass Spec Standard

Specifications

Product Data
Description	TIMM16 MS Standard C13 and N15-labeled recombinant protein (NP_057153)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202828
Predicted MW	13.8 kDa
Protein Sequence	Sequence Link (showhide) >RC202828 protein sequence Red=Cloning site Green=Tags(s) MAKYLAQIIVMGVQVVGRAFARALRQEFAASRAAADARGRAGHRSAAASNLSGLSLQEAQQILNVSKLSP EEVQKNYEHLFKVNDKSVGGSFYLQSKVVRAKERLDEELKIQAQEDREKGQMPHT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057153
RefSeq Size	600
RefSeq ORF	375
Synonyms	CGI-136; MAGMAS; SMDMDM; TIM16; TIMM16
Locus ID	51025
Cytogenetics	16p13.3
Summary	This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]

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