RNF34 (NM_025126) Human Mass Spec Standard

CAT#: PH303191

RNF34 MS Standard C13 and N15-labeled recombinant protein (NP_079402)



  View other "RNF34" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description RNF34 MS Standard C13 and N15-labeled recombinant protein (NP_079402)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203191
Predicted MW 41.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_079402
RefSeq Size 2055
RefSeq ORF 1116
Synonyms CARP-1; CARP1; hRFI; RFI; RIF; RIFF
Locus ID 80196
Cytogenetics 12q24.31
Summary The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
Protein Families Druggable Genome
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