Lin28 (LIN28A) (NM_024674) Human Mass Spec Standard

CAT#: PH303397

LIN28A MS Standard C13 and N15-labeled recombinant protein (NP_078950)



  View other "Lin28" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of lin-28 homolog (LIN28)
    • 100 ug

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Rabbit polyclonal LIN28A Antibody (Center)
    • 400 ul

CNY 6,314.00

Specifications

Product Data
Description LIN28A MS Standard C13 and N15-labeled recombinant protein (NP_078950)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203397
Predicted MW 22.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_078950
RefSeq Size 4014
RefSeq ORF 627
Synonyms CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
Locus ID 79727
Cytogenetics 1p36.11
Summary This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]
Protein Families Transcription Factors
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