SPSB1 (NM_025106) Human Mass Spec Standard

CAT#: PH303673

SPSB1 MS Standard C13 and N15-labeled recombinant protein (NP_079382)



  View other "SPSB1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description SPSB1 MS Standard C13 and N15-labeled recombinant protein (NP_079382)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203673
Predicted MW 30.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_079382
RefSeq Size 3130
RefSeq ORF 819
Synonyms SSB-1; SSB1
Locus ID 80176
Cytogenetics 1p36.22
Summary Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876).[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
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