RGS13 (NM_144766) Human Mass Spec Standard

Specifications

Product Data
Description	RGS13 MS Standard C13 and N15-labeled recombinant protein (NP_658912)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203804
Predicted MW	19.1 kDa
Protein Sequence	Sequence Link (showhide) >RC203804 protein sequence Red=Cloning site Green=Tags(s) MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETY KKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRF LKSEMYQKLLKTMQSNNSF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_658912
RefSeq Size	1538
RefSeq ORF	477
Locus ID	6003
Cytogenetics	1q31.2
Summary	The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome

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