PUS7 (NM_019042) Human Mass Spec Standard

CAT#: PH303902

PUS7 MS Standard C13 and N15-labeled recombinant protein (NP_061915)



  View other "PUS7" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description PUS7 MS Standard C13 and N15-labeled recombinant protein (NP_061915)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203902
Predicted MW 75 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_061915
RefSeq Size 3484
RefSeq ORF 1983
Synonyms IDDABS
Locus ID 54517
Cytogenetics 7q22.3
Summary Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141).[UniProtKB/Swiss-Prot Function]
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