serum amyloid A2 (SAA2) (NM_030754) Human Mass Spec Standard

Specifications

Product Data
Description	SAA2 MS Standard C13 and N15-labeled recombinant protein (NP_110381)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204977
Predicted MW	13.5 kDa
Protein Sequence	Sequence Link (showhide) >RC204977 protein sequence Red=Cloning site Green=Tags(s) MKLLTGLVFCSLVLSVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGA WAAEVISNARENIQRLTGHGAEDSLADQAANKWGRSGRDPNHFRPAGLPEKY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_110381
RefSeq Size	594
RefSeq ORF	366
Synonyms	SAA; SAA1
Locus ID	6289
Cytogenetics	11p15.1
Summary	This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. [provided by RefSeq, Jul 2020]
Protein Families	Druggable Genome

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