CD32A (FCGR2A) (NM_021642) Human Mass Spec Standard

Specifications

Product Data
Description	FCGR2A MS Standard C13 and N15-labeled recombinant protein (NP_067674)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205786
Predicted MW	34.7 kDa
Protein Sequence	Sequence Link (showhide) >RC205786 representing NM_021642 Red=Cloning site Green=Tags(s) MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESD SIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIML RCHSWKDKPLVKVTFFQNGKSQKFSRLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMG SSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDY ETADGGYMTLNPRAPTDDDKNIYLTLPPNDHVNSNN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_067674
RefSeq Size	2411
RefSeq ORF	948
Synonyms	CD32; CD32A; CDw32; FCG2; FcGR; FCGR2; FCGR2A1; IGFR2
Locus ID	2212
Cytogenetics	1q23.3
Summary	This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

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