Neurofilament (NEFL) (NM_006158) Human Mass Spec Standard
CAT#: PH305920
NEFL MS Standard C13 and N15-labeled recombinant protein (NP_006149)
View other "Neurofilament" proteins (6)
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CNY 19,520.00
Cited in 2 publications. |
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Description | NEFL MS Standard C13 and N15-labeled recombinant protein (NP_006149) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC205920 |
Predicted MW | 61.5 kDa |
Protein Sequence |
>RC205920 protein sequence
Red=Cloning site Green=Tags(s) MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLEN LDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYE QEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELE KRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWF KSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDT INKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFG RSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEE AAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKKD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_006149 |
RefSeq Size | 3854 |
RefSeq ORF | 1629 |
Synonyms | CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110 |
Locus ID | 4747 |
Cytogenetics | 8p21.2 |
Summary | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
Adipose-Derived Mesenchymal Stem Cells From a Hypoxic Culture Improve Neuronal Differentiation and Nerve Repair
,null,
Frontiers in Cell and Developmental Biology
,PubMed ID 33996818
[NEFL]
|
Mesenchymal stem cells from a hypoxic culture improve nerve regeneration.
,null,
Journal of tissue engineering and regenerative medicine
,PubMed ID 32976700
[NEFL]
|
Documents
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蛋白相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC416829 | NEFL HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY416829 | Transient overexpression lysate of neurofilament, light polypeptide (NEFL) |
CNY 3,080.00 |
|
TP305920 | Recombinant protein of human neurofilament, light polypeptide (NEFL), 20 µg |
CNY 2,900.00 |
|
TP762354 | Purified recombinant protein of Human neurofilament, light polypeptide (NEFL), Met1-Thr360, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 1,950.00 |
|
TP762419 | Purified recombinant protein of Human neurofilament, light polypeptide (NEFL), Ser2-Glu90, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 1,950.00 |
|
TP762429 | Purified recombinant protein of Human neurofilament, light polypeptide (NEFL), Glu90-Leu400, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 1,950.00 |
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