KCNK17 (NM_031460) Human Mass Spec Standard

Specifications

Product Data
Description	KCNK17 MS Standard C13 and N15-labeled recombinant protein (NP_113648)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206399
Predicted MW	36.9 kDa
Protein Sequence	Sequence Link (showhide) >RC206399 protein sequence Red=Cloning site Green=Tags(s) MYRPRARAAPEGRVRGCAVPGTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLD RPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVG IPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLLFSHMEGWSYTE GFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHS SKEDFKSQSWRQGPDREPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_113648
RefSeq Size	1589
RefSeq ORF	996
Synonyms	K2p17.1; TALK-2; TALK2; TASK-4; TASK4
Locus ID	89822
Cytogenetics	6p21.2
Summary	The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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