GCAP1 (GUCA1A) (NM_000409) Human Mass Spec Standard

Specifications

Product Data
Description	GUCA1A MS Standard C13 and N15-labeled recombinant protein (NP_000400)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206595
Predicted MW	22.9 kDa
Protein Sequence	Sequence Link (showhide) >RC206595 protein sequence Red=Cloning site Green=Tags(s) MGNVMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGY IDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIQAIRAINPCSDTTMTAEEFTDTVF SKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQDEEGADEAAEAAG TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000400
RefSeq Size	1918
RefSeq ORF	603
Synonyms	GUCA1A; GUCA1ANB-GUCA1A
Locus ID	2978
Cytogenetics	6p21.1
Summary	This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. provided by RefSeq, Jul 2020]
Protein Families	Druggable Genome
Protein Pathways	Olfactory transduction

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