CD42a (GP9) (NM_000174) Human Mass Spec Standard

Specifications

Product Data
Description	GP9 MS Standard C13 and N15-labeled recombinant protein (NP_000165)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206597
Predicted MW	19.1 kDa
Protein Sequence	Sequence Link (showhide) >RC206597 protein sequence Red=Cloning site Green=Tags(s) MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLANNSLQSVPPGA FDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQ ASWVRPGVLWDVALVTVAALGLALLAGLLCATTEALD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000165
RefSeq Size	911
RefSeq ORF	531
Synonyms	CD42a; GPIX
Locus ID	2815
Cytogenetics	3q21.3
Summary	This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ECM-receptor interaction, Hematopoietic cell lineage

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