Cryptochrome I (CRY1) (NM_004075) Human Mass Spec Standard
CAT#: PH307152
CRY1 MS Standard C13 and N15-labeled recombinant protein (NP_004066)
View other "Cryptochrome I" proteins (3)
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CNY 19,520.00
Specifications
Product Data | |
Description | CRY1 MS Standard C13 and N15-labeled recombinant protein (NP_004066) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC207152 |
Predicted MW | 66.4 kDa |
Protein Sequence |
>RC207152 protein sequence
Red=Cloning site Green=Tags(s) MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLN SRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIE LNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVW PGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNS SPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQE GWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQ LSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTG LSGGKRPSQEEDTQSIGPKVQRQSTN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_004066 |
RefSeq Size | 3310 |
RefSeq ORF | 1758 |
Synonyms | DSPD; PHLL1 |
Locus ID | 1407 |
Cytogenetics | 12q23.3 |
Summary | This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014] |
Protein Families | Druggable Genome |
Protein Pathways | Circadian rhythm - mammal |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418241 | CRY1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY418241 | Transient overexpression lysate of cryptochrome 1 (photolyase-like) (CRY1) |
CNY 3,080.00 |
|
TP307152 | Recombinant protein of human cryptochrome 1 (photolyase-like) (CRY1), 20 µg |
CNY 2,900.00 |
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