EXTL2 (NM_001439) Human Mass Spec Standard

Specifications

Product Data
Description	EXTL2 MS Standard C13 and N15-labeled recombinant protein (NP_001430)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207406
Predicted MW	37.5 kDa
Protein Sequence	Sequence Link (showhide) >RC207406 protein sequence Red=Cloning site Green=Tags(s) MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIM QTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPE LETNAVLMVDDDTLISTTDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSM VLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGY SGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001430
RefSeq Size	3217
RefSeq ORF	990
Synonyms	EXTR2
Locus ID	2135
Cytogenetics	1p21.2
Summary	Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane
Protein Pathways	Heparan sulfate biosynthesis

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