IKZF3 (NM_012481) Human Mass Spec Standard

CAT#: PH307547

IKZF3 MS Standard C13 and N15-labeled recombinant protein (NP_036613)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description IKZF3 MS Standard C13 and N15-labeled recombinant protein (NP_036613)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207547
Predicted MW 58 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_036613
RefSeq Size 9686
RefSeq ORF 1527
Synonyms AIO; AIOLOS; ZNFN1A3
Locus ID 22806
Cytogenetics 17q12-q21.1
Summary This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
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