CA7 (NM_001014435) Human Mass Spec Standard

Specifications

Product Data
Description	CA7 MS Standard C13 and N15-labeled recombinant protein (NP_001014435)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207575
Predicted MW	23.5 kDa
Protein Sequence	Sequence Link (showhide) RC207575
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001014435
RefSeq Size	1710
RefSeq ORF	627
Synonyms	CA-VII; CAVII
Locus ID	766
Cytogenetics	16q22.1
Summary	Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]
Protein Families	Druggable Genome
Protein Pathways	Nitrogen metabolism

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