Peptide YY (PYY) (NM_004160) Human Mass Spec Standard

Specifications

Product Data
Description	PYY MS Standard C13 and N15-labeled recombinant protein (NP_004151)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208334
Predicted MW	11.1 kDa
Protein Sequence	Sequence Link (showhide) >RC208334 protein sequence Red=Cloning site Green=Tags(s) MVFVRRPWPALTTVLLALLVCLGALVDAYPIKPEAPGEDASPEELNRYYASLRHYLNLVTRQRYGKRDGP DRLLSKTFFPDGEDRPVRSRSEGPDLW TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004151
RefSeq Size	1069
RefSeq ORF	291
Synonyms	PYY-I; PYY1
Locus ID	5697
Cytogenetics	17q21.31
Summary	This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]
Protein Families	Secreted Protein, Transmembrane

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