SMAD3 (NM_005902) Human Mass Spec Standard

CAT#: PH308749

SMAD3 MS Standard C13 and N15-labeled recombinant protein (NP_005893)



  View other "SMAD3" proteins (6)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description SMAD3 MS Standard C13 and N15-labeled recombinant protein (NP_005893)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208749
Predicted MW 47.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005893
RefSeq Size 6256
RefSeq ORF 1275
Synonyms HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3
Locus ID 4088
Cytogenetics 15q22.33
Summary The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, Nov 2019]
Protein Families Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
Protein Pathways Adherens junction, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway, Wnt signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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