LAP2 (TMPO) (NM_001032283) Human Mass Spec Standard

CAT#: PH308781

TMPO MS Standard C13 and N15-labeled recombinant protein (NP_001027454)



  View other "LAP2" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description TMPO MS Standard C13 and N15-labeled recombinant protein (NP_001027454)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208781
Predicted MW 50.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001027454
RefSeq Size 4186
RefSeq ORF 1362
Synonyms CMD1T; LAP2; LEMD4; PRO0868; TP
Locus ID 7112
Cytogenetics 12q23.1
Summary Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]
Protein Families Stem cell - Pluripotency, Transmembrane
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