AKR1C2 (NM_205845) Human Mass Spec Standard

CAT#: PH309081

AKR1C2 MS Standard C13 and N15-labeled recombinant protein (NP_995317)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Rabbit polyclonal anti-AKR1C2 antibody
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Transient overexpression lysate of aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) (AKR1C2), transcript variant 3
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description AKR1C2 MS Standard C13 and N15-labeled recombinant protein (NP_995317)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209081
Predicted MW 36.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_995317
RefSeq Size 3521
RefSeq ORF 969
Synonyms AKR1C-pseudo; BABP; DD; DD-2; DD/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD
Locus ID 1646
Cytogenetics 10p15.1
Summary This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Protein Families Druggable Genome
Protein Pathways Metabolism of xenobiotics by cytochrome P450
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