ZCCHC8 (NM_017612) Human Mass Spec Standard

CAT#: PH309528

ZCCHC8 MS Standard C13 and N15-labeled recombinant protein (NP_060082)



  View other "ZCCHC8" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ZCCHC8 MS Standard C13 and N15-labeled recombinant protein (NP_060082)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209528
Predicted MW 78.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_060082
RefSeq Size 4260
RefSeq ORF 2121
Synonyms PFBMFT5
Locus ID 55596
Cytogenetics 12q24.31
Summary This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]
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