Ferritin Heavy Chain (FTH1) (NM_002032) Human Mass Spec Standard

Specifications

Product Data
Description	FTH1 MS Standard C13 and N15-labeled recombinant protein (NP_002023)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209845
Predicted MW	21.2 kDa
Protein Sequence	Sequence Link (showhide) >RC209845 protein sequence Red=Cloning site Green=Tags(s) MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKL MKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLN EQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002023
RefSeq Size	1245
RefSeq ORF	549
Synonyms	FHC; FTH; FTHL6; HFE5; PIG15; PLIF
Locus ID	2495
Cytogenetics	11q12.3
Summary	This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Porphyrin and chlorophyll metabolism

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