HNF1 alpha (HNF1A) (NM_000545) Human Mass Spec Standard

CAT#: PH311201

HNF1A MS Standard C13 and N15-labeled recombinant protein (NP_000536)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description HNF1A MS Standard C13 and N15-labeled recombinant protein (NP_000536)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211201
Predicted MW 67.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000536
RefSeq Size 3249
RefSeq ORF 1893
Synonyms HNF-1A; HNF1; HNF1alpha; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1
Locus ID 6927
Cytogenetics 12q24.31
Summary The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Protein Pathways Maturity onset diabetes of the young
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