Inhibin beta C chain (INHBC) (NM_005538) Human Mass Spec Standard

Specifications

Product Data
Description	INHBC MS Standard C13 and N15-labeled recombinant protein (NP_005529)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC211922
Predicted MW	38.21 kDa
Protein Sequence	Sequence Link (showhide) >RC211922 representing NM_005538 Red=Cloning site Green=Tags(s) MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVSRA ALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL PSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSSV ILGGAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQC PLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTAQRPLSLLYYDRDSNIVKTDIPDMVVEACG CS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005529
RefSeq Size	1990
RefSeq ORF	1056
Synonyms	IHBC
Locus ID	3626
Cytogenetics	12q13.3
Summary	This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

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