IGF1 (NM_000618) Human Mass Spec Standard

CAT#: PH312527

IGF1 MS Standard C13 and N15-labeled recombinant protein (NP_000609)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description IGF1 MS Standard C13 and N15-labeled recombinant protein (NP_000609)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212527
Predicted MW 17.03 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000609
RefSeq Size 7260
RefSeq ORF 459
Synonyms IGF; IGF-I; IGFI; MGF
Locus ID 3479
Cytogenetics 12q23.2
Summary The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer
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