NPHS2 (NM_014625) Human Mass Spec Standard

Specifications

Product Data
Description	NPHS2 MS Standard C13 and N15-labeled recombinant protein (NP_055440)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC212676
Predicted MW	42 kDa
Protein Sequence	Sequence Link (showhide) >RC212676 representing NM_014625 Red=Cloning site Green=Tags(s) MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEV RGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLG HLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHV SKAVQFLVQTTMKRLLAHRSLTEILLERKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAV EAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCL SSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055440
RefSeq Size	1853
RefSeq ORF	1149
Synonyms	PDCN; SRN1
Locus ID	7827
Cytogenetics	1q25.2
Summary	This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Protein Families	Transmembrane

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