AGXT (NM_000030) Human Mass Spec Standard

Specifications

Product Data
Description	AGXT MS Standard C13 and N15-labeled recombinant protein (NP_000021)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC212899
Predicted MW	43 kDa
Protein Sequence	Sequence Link (showhide) >RC212899 protein sequence Red=Cloning site Green=Tags(s) MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQT RNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVE EGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKA LNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIA EQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGG LGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKKKL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000021
RefSeq Size	1611
RefSeq ORF	1176
Synonyms	AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6
Locus ID	189
Cytogenetics	2q37.3
Summary	This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Alanine, aspartate and glutamate metabolism, Glycine, serine and threonine metabolism, Metabolic pathways

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