RS1 (NM_000330) Human Mass Spec Standard

Specifications

Product Data
Description	RS1 MS Standard C13 and N15-labeled recombinant protein (NP_000321)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC214267
Predicted MW	25.59 kDa
Protein Sequence	Sequence Link (showhide) >RC214267 representing NM_000330 Red=Cloning site Green=Tags(s) MSRKIEGFLLLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLG FESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQG RCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRI AIRMELLECVSKCA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000321
RefSeq Size	3046
RefSeq ORF	672
Synonyms	RS; XLRS1
Locus ID	6247
Cytogenetics	Xp22.13
Summary	This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq, Oct 2008]
Protein Families	Secreted Protein

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