BAIAP2 (NM_006340) Human Mass Spec Standard

CAT#: PH314570

BAIAP2 MS Standard C13 and N15-labeled recombinant protein (NP_006331)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description BAIAP2 MS Standard C13 and N15-labeled recombinant protein (NP_006331)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214570
Predicted MW 57.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006331
RefSeq Size 2129
RefSeq ORF 1560
Synonyms BAP2; FLAF3; IRSP53; WAML
Locus ID 10458
Cytogenetics 17q25.3
Summary The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
Protein Families Druggable Genome
Protein Pathways Adherens junction, Regulation of actin cytoskeleton
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