FOXP2 (NM_014491) Human Mass Spec Standard

CAT#: PH315021

FOXP2 MS Standard C13 and N15-labeled recombinant protein (NP_055306)



  View other "FOXP2" proteins (7)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Rabbit Polyclonal Anti-FOXP2 Antibody
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Transient overexpression lysate of forkhead box P2 (FOXP2), transcript variant 3
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Specifications

Product Data
Description FOXP2 MS Standard C13 and N15-labeled recombinant protein (NP_055306)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215021
Predicted MW 79.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_055306
RefSeq Size 6373
RefSeq ORF 2145
Synonyms CAGH44; SPCH1; TNRC10
Locus ID 93986
Cytogenetics 7q31.1
Summary This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Protein Families Transcription Factors
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