HDAC7 (NM_015401) Human Mass Spec Standard

Specifications

Product Data
Description	HDAC7 MS Standard C13 and N15-labeled recombinant protein (NP_056216)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215233
Predicted MW	106.6 kDa
Protein Sequence	Sequence Link (showhide) RC215233
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_056216
RefSeq Size	4301
RefSeq ORF	2973
Synonyms	HD7; HD7A; HDAC7A
Locus ID	51564
Cytogenetics	12q13.11
Summary	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transcription Factors

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.